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HVAC 7 min read May 28, 2026

Refrigerant Numbers Explained

How the R-number system encodes the molecule or the blend, and what the safety class, ODP, GWP, and glide actually tell you.

Every refrigerant carries an R-number assigned under ASHRAE Standard 34. It is not a product code, it is a description of the chemistry. Once you can read it, an unfamiliar number stops being a mystery and starts telling you what you are dealing with. This guide walks the rules for single compounds first, then blends, then the safety class and the environmental numbers.

Single Compounds: Counting Atoms

For a single-compound refrigerant the digits count atoms in the molecule:

  • The ones digit is the number of fluorine atoms.
  • The tens digit is the number of hydrogen atoms plus one.
  • The hundreds digit is the number of carbon atoms minus one (left off when it is zero, which is the single-carbon methane series).

Chlorine fills whatever bonds are left over. Run R-22 through it: ones digit 2 (two fluorines), tens digit 2 (one hydrogen), no hundreds digit (one carbon). A single carbon has four bonds, minus one hydrogen and two fluorines leaves one chlorine. That is CHClF2, a hydrochlorofluorocarbon (HCFC). R-32 works out to one carbon, two hydrogens, two fluorines, no chlorine: a clean HFC.

HVAC

Refrigerant Designation Decoder

Decode any refrigerant R-number (R-410A, R-32, R-1234yf, R-22, R-744). Explains the ASHRAE 34 numbering rules digit by digit, then gives the chemical family, blend composition, safety class, ODP, GWP, temperature glide, and what the refrigerant replaces or is replaced by. Reuses ToolGrit's shared refrigerant dataset so the numbers match the P-T chart and charge tools.

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What the Family Tells You

The atoms determine the family, and the family tells you the environmental story:

  • CFC (chlorine, no hydrogen) and HCFC (chlorine and hydrogen) contain chlorine, which depletes ozone. These are the phased-out legacy refrigerants like R-12 and R-22.
  • HFC (hydrogen and fluorine, no chlorine) has zero ozone depletion but often a high global warming potential. R-134a and R-410A are HFCs.
  • HFO (an unsaturated HFC, with a carbon-carbon double bond) breaks down quickly in the atmosphere and has a very low GWP. R-1234yf is an HFO.
  • Hydrocarbons (R-290 propane) and inorganics (R-744 CO2) are natural refrigerants with very low GWP.

Blends: the 400 and 500 Series

When a refrigerant is a mixture, it gets a 400 or 500 series number instead of an atom-count number.

  • 400 series blends are zeotropic: the components boil at different temperatures, so the blend has temperature glide.
  • 500 series blends are azeotropic: they behave like a single compound, with negligible glide.

The numbers are assigned in order, so they do not encode the composition directly. The trailing capital letter (A, B, C) distinguishes blends made of the same components in different ratios. R-407C and R-407A are the same three components in different proportions.

Source: ANSI/ASHRAE Standard 34, Designation and Safety Classification of Refrigerants. The 700 series uses the molar mass, which is why R-744 is CO2 (molar mass 44) and R-717 is ammonia (17).

The Safety Class

The safety class is two parts. The letter is toxicity: A is lower toxicity, B is higher. The number is flammability: 1 is no flame propagation (non-flammable), 2L is mildly flammable with a low burning velocity, 2 is flammable, and 3 is highly flammable. So R-410A is A1 (non-flammable), R-32 and R-454B are A2L (mildly flammable), and propane R-290 is A3 (highly flammable).

Warning: A2L refrigerants are replacing A1 refrigerants for their lower GWP, but they are not non-flammable. Equipment, charge limits, and leak detection must match the A2L class per the applicable code. Do not assume an A2L is a drop-in for A1 equipment.

ODP, GWP, and Glide

ODP (ozone depletion potential) is referenced to CFC-11 at 1.0; modern refrigerants are zero. GWP (global warming potential) compares the gas to CO2 over 100 years, with CO2 at 1. A high GWP is why a refrigerant gets targeted by the phasedown: R-404A near 3922 leaks the CO2-equivalent of almost two tons per pound. Glide is the temperature spread of a zeotropic blend as it changes phase; it is why you charge a zeotrope from the liquid side and recover and recharge after a leak rather than topping off.

Calculators Referenced in This Guide

Emissions Live

Refrigerant Leak CO2 Equivalent Calculator

Calculate CO2 equivalent emissions from refrigerant leaks using EPA GWP values. Supports R-410A, R-134a, R-22, R-404A, R-407C, R-32, R-1234yf, and more. See annual GHG inventory impact in metric tons CO2e.

HVAC Live

Superheat & Subcooling Calculator

Calculate superheat and subcooling for HVAC/R system diagnostics. Supports R-410A, R-22, R-134a, R-404A, R-407C, R-32, and R-290 refrigerants with saturation temperature lookup from measured pressures.

HVAC Live

Refrigerant P-T Chart

Interactive pressure-temperature saturation chart for 13 common refrigerants including R-410A, R-22, R-134a, R-454B, and R-32. Bubble/dew point for R-407C, superheat/subcooling reference.